The biggest issue is getting "meaningful" minutes to the ones who need it. No matter the depth, some will better than others and should be out there more as a result. It won't be an issue through district and most of the playoffs though. Silsbee is just that much better than those opponents. There will be some great action predistrict and Silsbee may take some lumps there (Fort Bend and San Antonio if the better teams play in that one).
You bring up a great point about finding which groups play well together. The issue there, at least in my experience, is that is a fluid concept and can literally change from game to game.